Metagenome Analysis
Unlock the complex world of microbial communities. Utilizing 16S/18S/ITS and Shotgun Metagenomics, we provide end-to-end bioinformatics answering "Who is there?" and "What are they doing?".
What we offer
What you receive
Analysis capabilities
Taxonomic diversity profiling
Amplicon or shotgun data classification from phylum to species level.
Functional pathway analysis
Shotgun data mapped to reconstruct active biochemical pathways — nitrogen and carbon cycling and more — within the community.
AMR & enzyme discovery
Targeted screening against the Comprehensive Antibiotic Resistance Database (CARD) and mining for industrial biocatalysts.
Study environments
Clinical microbiome
Gut, skin and oral microbiome profiling in relation to disease states (dysbiosis).
Environmental
Soil, ocean and extreme-environment metagenomics for ecological monitoring.
Industrial / Agriculture
Bioremediation tracking, fermenter community dynamics and plant rhizobiome analysis.
Instrument compatibility
Illumina MiSeq (V2/V3), NextSeq 550, Thermo Fisher Ion S5, GeneMind GenoLab M.
Illumina NovaSeq X, MGI T7, Oxford Nanopore (GridION / PromethION) for real-time surveillance.
Data quality & AI pipeline
Tools & databases
Service tiers & deliverables
Amplicon Profiling
16S / 18S / ITS diversity analysis
OTU/ASV tables, Krona charts, alpha/beta diversity plots, LEfSe biomarker discovery.
Request a QuoteShotgun Functional Analysis
Comprehensive strain & pathway mapping
Deep taxonomic profiles, functional gene counts (SEED/KEGG), AMR (CARD) & virulence factor profiles.
Request a QuotePublication support included
Full metadata analysis integration, robust statistical validation (PERMANOVA / ANOSIM), methodology write-ups and figure generation tailored for high-impact journals like Microbiome or the ISME Journal.
Workflow
Sample & QC
Extraction, QC and library prep under documented, standardised protocols.
Sequencing / Processing
Calibrated runs and pipelines on validated platforms.
Bioinformatics
HPC-backed assembly, alignment, variant calling and annotation.
Report & Insight
Publication-ready reports, with a dedicated project manager throughout.
Frequently asked
Amplicon (16S/18S/ITS) profiles community composition cost-effectively to genus level. Shotgun sequences all DNA for species/strain resolution plus functional potential such as AMR and pathway content.
Get a tailored quote
Tell us your sample type, scope and timelines — we'll respond within one business day.
Request a QuoteOriginal Page Content
Metagenome Analysis
Unlock the complex world of microbial communities. Utilizing 16S/18S/ITS and Shotgun Metagenomics, we provide end-to-end bioinformatics answering "Who is there?" and "What are they doing?".
Analysis Capabilities
1. Taxonomic Diversity Profiling
Amplicon or Shotgun data classification (Phylum to Species).
- Alpha Diversity: Chao1, Shannon, Simpson (Richness & Evenness).
- Beta Diversity: PCoA, NMDS (Bray-Curtis, UniFrac).
2. Functional Pathway Analysis
Shotgun data mapped to reconstruct active biochemical pathways (Nitrogen, Carbon cycling, etc.) within the community.
3. AMR & Enzyme Discovery
Targeted screening against the Comprehensive Antibiotic Resistance Database (CARD) and mining for industrial biocatalysts.
Study Environments
-
Clinical Microbiome: Gut, skin, and oral microbiome profiling in relation to disease states (Dysbiosis).
-
Environmental: Soil, ocean, and extreme environment metagenomics for ecological monitoring.
-
Industrial/Agriculture: Bioremediation tracking, fermenter community dynamics, and plant rhizobiome analysis.
Instrument Compatibility
Amplicon Platforms
Illumina MiSeq (V2/V3), NextSeq 550, Thermo Fisher Ion S5, GeneMind GenoLab M.
Shotgun Metagenomics
Illumina NovaSeq X, MGI T7, Oxford Nanopore (GridION/PromethION) for real-time surveillance.
Data Quality & AI Pipeline
- • 16S Data: 100k - 500k reads/sample, Q30 > 75%
- • Shotgun Data: 5-10GB Raw Data/sample, Q30 > 80%
- • AI Utilization: We apply Kraken2 ML-based algorithms for rapid taxonomic classification and MetaBat2 for predictive functional binning of MAGs (Metagenome-Assembled Genomes).
Service Tiers & Deliverables
Amplicon Profiling
16S / 18S / ITS Diversity Analysis
TAT: 10 - 15 Days
Deliverables: OTU/ASV Tables, Krona Charts, Alpha/Beta Diversity Plots, LEfSe Biomarker Discovery.
Shotgun Functional Analysis
Comprehensive Strain & Pathway Mapping
TAT: 3 - 4 Weeks
Deliverables: Deep Taxonomic Profiles, Functional Gene Counts (SEED/KEGG), AMR (CARD) & Virulence Factor Profiles.
Publication Support Included
Full metadata analysis integration, robust statistical validation (PERMANOVA/ANOSIM), methodology write-ups, and figure generation tailored for high-impact journals like Microbiome or ISME Journal.