Proteomics Services in India – Quantitative & Functional Analysis
Comprehensive protein identification, quantification, PTM analysis, and biomarker discovery using high-resolution mass spectrometry.
What is Proteomics?
Proteomics is the large-scale study of the proteome — the complete set of proteins expressed by a genome, cell, tissue, or organism at a given time. Unlike genomics, which studies static DNA sequences, proteomics captures dynamic protein expression, interactions, modifications, and localization.
Our platform bridges genomics and phenotype, enabling deeper insights into disease mechanisms, drug response, and biological pathways.
Workflow / Steps
Consultation & Experimental Design
Defining biological question and statistical power
Protein Extraction & Sample Prep
Optimized protocols for cells, tissues, biofluids
Enzymatic Digestion
Trypsin, Lys-C, or multi-protease strategies
Peptide Fractionation & Enrichment
High-pH RP fractionation, PTM-specific
High-Resolution LC-MS/MS Analysis
Orbitrap or Q-TOF platforms
Data Analysis & Interpretation
MaxQuant, Proteome Discoverer
Biological Interpretation & Reporting
Pathway analysis, GO enrichment
Request Proteomics Study Quote
Ready to explore the proteome? Contact us to discuss your experimental design and get a personalized quote. **Yaazh Xenomics Pvt Ltd** — Module No. 103, TICEL BIOPARK Phase – III, Maruthamalai Road, Coimbatore – 641046, Tamil Nadu, India. Phone: +91 99431 32020 | +91 95002 45454. Email: info@yaazhxenomics.com
Our Advanced Proteomics Capabilities
1. Shotgun / Discovery Proteomics
High-throughput identification of thousands of proteins in complex samples using data-dependent acquisition (DDA). Ideal for unbiased proteome profiling, differential expression analysis, and novel protein discovery.
2. Quantitative Proteomics
Label-Free Quantification (LFQ) for cost-effective quantification; TMT / iTRAQ Multiplexing (up to 18-plex); SILAC metabolic labeling for cell culture.
3. Post-Translational Modification (PTM)
Specialized workflows for phosphorylation, acetylation, ubiquitination, glycosylation using enrichment strategies followed by high-resolution LC-MS/MS.
4. Targeted Proteomics (PRM / MRM)
Highly sensitive and specific quantification of selected proteins/peptides using PRM or MRM on triple quadrupole or high-resolution instruments.
Specialised Proteomic Services
Yaazh Xenomics serves as a one-stop-shop for proteomic services that are critical for gene expression study and analysis.
Key Applications
- Biomarker discovery in cancer, neurodegenerative, and metabolic diseases
- Drug target identification and mechanism of action studies
- Proteome profiling of disease vs. healthy states
- Host-pathogen interaction studies
- Quality control of recombinant proteins and biologics
- Plant proteomics and agricultural biotechnology
Technologies, Tools & Why Choose Us
High-resolution mass spectrometers: Orbitrap Exploris / Q Exactive series
Nano-flow liquid chromatography systems: For high-sensitivity peptide separation
Data processing software: MaxQuant, Proteome Discoverer, Spectronaut, DIA-NN
Downstream bioinformatics: Perseus, STRING, Cytoscape
Why Choose Yaazh Xenomics?: Expert team with strong background in mass spectrometry; robust quality control and reproducible results; advanced bioinformatics support with biological interpretation; end-to-end support from experimental design to publication.